Comments Share what you think. View all. Bing Site Web Enter search term: Search. Ad Feature 'That waistband is fishy! How one supermarket is keeping pace with surge in demand for plant-based food Ad Feature Sex and the City fans get emotional over seeing Willie Garson for the last time as Stanford Blatch in trailer for And Just Like That Stay home to protect the NHS even when Covid is dropping?
Boris compares Europe's escalating Covid outbreak to 'storm clouds' that could hit Britain next as daily UK Ex-England star Matt Le Tissier is blasted for sharing anti-vaccine conspiracy theories amid fears online GP who wants doctors to stop 'vital' unfunded work may be next head of 'militant' union panel considering Care home boss breaks down in tears after having to sack SIX members of staff over No10's 'no jab, no job' Damon Albarn's solo album is a blend of laidback introspection and Blur-worthy pop Tiger King As it roars back, what does the woman Joe Exotic wanted dead have to say?
Kuzma, C. Shin, L. Zaccheus, M. Toddler allegedly dispensed overdose of cough syrup. Thai, H. Gastroenteritis or the stomach flu is a viral or bacterial infection that causes irritation and inflammation of the stomach and intestines.
Here are 4 orthopaedic conditions in children to be aware of. Kneecap dislocation in children can be a worrisome condition. Read on to understand what a learn what is patellar dislocation, what are its symptoms and what you need to do immediately. Returning to some semblance of normalcy may be on the horizon, but what about women who are pregnant or are breastfeeding?
Learn why pre-natal screenings are important and how it can help pregnant mothers achieve a full-term pregnancy. COVID vaccines have been administered on millions around the world, with mostly positive outcomes.
As adults around the world scramble to get vaccinated, do the benefits apply to children? A medical emergency is something no parent hopes for. Did you know that asthma can be managed effectively with the right care? Read on to understand the various asthma medicines and the correct way to use them.
Deciding whether a natural or caesarean delivery is right for you is a question you should discuss with your doctor. Especially when it considers your personal circumstances and medical history. Learn the symptoms, and find out how to prevent these infections. Vaccines protect your baby against diseases which can cause disability and even death. Children can develop allergic reactions to food. This article discusses the symptoms and treatment of food allergy and differentiates food allergy from food intolerance.
Cystoscopy is a procedure done to evaluate your urinary bladder and urethra. You can prepare for this procedure by understanding what it is for and how it is done. Parents have been warned that giving children paracetamol-based medicines such as Calpol and Disprol too often could lead to serious health issues later in life.
Leading paediatrician and professor of general paediatrics at University College London, Alastair Sutcliffe, said parents were overusing paracetamol to treat mild fevers. As a result, the risk of developing asthma, as well as kidney, heart and liver damage is heightened, according to the Sunday Times.
They seem to fear fever as an illness, per se, which it is not. There is evidence that the excess usage of paracetamol is associated with increased rates of asthma, increased rates of liver damage, but less widely known, kidney and heart damage. NAC may be stopped if started before an appropriate paracetamol level is done, if the level is below the treatment line when the nomogram is valid and the patient has normal LFTs and is asymptomatic.
NAC is usually continued if blood tests are still significantly abnormal after the first course. The dose depends on local protocols but is often at the rate of the third last given bag.
Patients should be advised to return if vomiting occurs after discharge. The treatment of patients presenting more than 24 hours after ingestion is controversial. A measurable paracetamol concentration more than 24 hours after ingestion either indicates a very large overdose, or suggests a mistake in time of ingestion, or a staggered overdose.
A full course of antidotal therapy should normally be given to patients in whom paracetamol is detected. Paracetamol is the most common drug taken in overdose during pregnancy [ 10 ].
The resulting toxic metabolites can cross the placenta and lead to hepatocellular necrosis of maternal and fetal liver cells. NAC can bind the toxic metabolites in the mother and fetal circulation as it crosses the placenta. NAC appears to be safe during pregnancy and therefore should be administered. More recently, a dynamic online prediction model has been made available, based on prospective data including analysis of more than 20 daily variables sequentially assessed for three days after ICU admission [ 6 ].
Although liver transplantation only has a limited application, patients must be identified as early as possible, preferably on the second day [ 12 ]. Current data indicate a poor prognosis if:. Liver transplantation is probably contra-indicated in patients with severe hypotension, severe cerebral oedema and serious infection. Br J Clin Pharmacol. Epub Jan Molloy P, Chambers R, Cork T ; How well are national guidelines relating to the general sales of aspirin and paracetamol, adhered to by retail stores: a mystery shopper study.
BMJ Open. Deaths related to drug poisoning in England and Wales: registrations ; Office for National Statistics. Br J Gen Pract. Epub Sep Hawton K et al ; Impact of different pack sizes of paracetamol in the United Kingdom and Ireland on intentional overdoses: a comparative study.
Biomed central Clin Toxicol Phila. A critical review of the literature. Eur J Clin Pharmacol.
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